Featuring IntellxxDNA and The Carroll Institute’s Advanced Genomic Approach

Last Updated: October 2025

While most people have heard of basic genetic tests like APOE-4 for Alzheimer’s risk, few realize how much more can be learned through advanced genomic analysis. The truth is, traditional genetic testing offers only a single piece of the puzzle. In contrast, IntellxxDNA® provides a comprehensive, clinical-grade look at hundreds of genes that influence brain health, inflammation, detoxification, and metabolism. These insights allow for truly personalized strategies to slow, and in many cases, reverse cognitive decline.

At The Carroll Institute in Sarasota, Dr. Garland Glenn, DC, PhD, AFMC is the only IntellxxDNA-certified clinician in the Sarasota area. This advanced training gives him exclusive access to the most detailed genomic panels available—panels specifically designed to uncover the genetic factors that contribute to Alzheimer’s disease and other forms of cognitive decline.

Going Beyond APOE-4

Most physicians who discuss “genetic testing” for Alzheimer’s are referring to a single gene: APOE. While the APOE-4 variant does increase risk for Alzheimer’s, it represents only one small part of a much larger genetic network. Therefore, relying solely on APOE status provides limited and often misleading information. As a result, patients are left without actionable steps for prevention or recovery.

IntellxxDNA testing, however, analyzes over 700 genes across multiple biological systems—including inflammation, mitochondrial health, detoxification, lipid metabolism, and neurotransmitter function. Consequently, this broader genetic insight helps us uncover why cognitive decline is happening and how to modify those risks through targeted nutrition, lifestyle, and therapeutic interventions.

Exclusive to Trained Clinicians

Unlike direct-to-consumer DNA tests, IntellxxDNA® is available only to healthcare professionals who have completed rigorous genomic and clinical training. This ensures that the data is interpreted correctly and applied ethically. Therefore, even if your doctor knows about IntellxxDNA, they cannot access or interpret this testing unless they are certified through the Intellxx clinician training program.

Dr. Glenn completed this advanced certification in order to integrate genomic science into the Bredesen ReCODE Protocol and Functional Medicine framework. This allows him to connect genetic data with metabolic and environmental findings, creating a comprehensive, individualized brain health plan.

How DNA Insights Guide Treatment

DNA testing does not determine your destiny—it helps you understand your body’s blueprint so you can make better decisions. Through IntellxxDNA analysis, Dr. Glenn identifies both risks and protective genetic variants that influence how your brain ages and functions. From there, specific, evidence-based interventions are developed to optimize gene expression.

• Detoxification genes: Reveal how efficiently your body removes heavy metals, mold toxins, and environmental chemicals.
• Methylation genes: Affect neurotransmitter balance, DNA repair, and homocysteine metabolism.
• Inflammation genes: Influence chronic inflammation and immune regulation, impacting memory and focus.
• Mitochondrial and energy genes: Regulate how well your neurons produce ATP and maintain function under stress.
• Lipid and cholesterol metabolism genes: Determine how efficiently your brain processes fats for cell membranes and myelin repair.
• Oxidative stress genes: Show your capacity to neutralize free radicals and prevent cellular aging.

By identifying these patterns, The Carroll Institute can personalize nutrition, supplements, and lifestyle changes that counteract genetic weaknesses and amplify strengths. In other words, your genes reveal what your brain needs most to heal.

DNA Testing and the ReCODE Protocol

The IntellxxDNA cognitive panel aligns seamlessly with the ReCODE Protocol. While ReCODE identifies metabolic and biochemical drivers of decline, IntellxxDNA reveals the genetic predispositions behind those imbalances. Consequently, this combined approach allows for precision-level treatment planning—addressing both the triggers and the tendencies behind cognitive decline.

For example, if a patient carries genetic variants that impair detoxification, their treatment plan might include enhanced liver support and targeted antioxidant therapy. Likewise, if mitochondrial function genes show reduced efficiency, specific nutrients like CoQ10 or PQQ can be used to optimize brain energy production. This level of personalization is what makes The Carroll Institute’s approach so effective.

Empowering Patients Through Knowledge

Genetic data can be incredibly empowering when used correctly. It gives patients a clear understanding of how their unique biology influences their brain health—and, more importantly, what to do about it. Rather than viewing genes as fate, Dr. Glenn helps patients see them as functional roadmaps for prevention and repair.

In most cases, we cannot change the genes we’re born with, but we can absolutely change how those genes are expressed. Through lifestyle, nutrition, detoxification, hormone balance, and neurorehabilitation, it is possible to “turn down” harmful gene activity and “turn up” protective ones. This is the future of personalized cognitive medicine—and it’s available today.

Next Steps: Discover Your Genetic Blueprint

If you’re experiencing brain fog, memory changes, or a family history of Alzheimer’s disease, understanding your genetic profile could change everything. Book a Discovery Call with The Carroll Institute to learn how DNA testing through IntellxxDNA can uncover the precise factors affecting your brain—and create a plan to protect it for years to come.

Sources

• IntellxxDNA: For Patients
• Reversal of Cognitive Decline — NIH (2014)
• Precision Medicine and Alzheimer’s — NIH (2023)

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